How to Scale DNA Production Effectively to Meet the Needs of Genetic Medicines DNA is the blueprint of life, carrying the molecular instructions that tell every cell how to…
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In this session, Elena Stoyanova, PhD (Touchlight) introduces mbDNA™ (Megabulb DNA), a novel single-stranded circular DNA template featuring a customizable stem region and fully user-defined sequence. Chesney Michels, PhD (ElevateBio)…
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MegaBulb DNA: Enabling better non-viral gene therapy with mbDNA – a cell-free circular ssDNA
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CRISPR HDR Breakthrough with mbDNA™: ssDNA Template Boosts Cell Viability & Scalability CRISPR has transformed our ability to edit genomes, enabling targeted insertions, deletions, and base corrections. Yet…
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mbDNA™ is a synthetic, circular single-stranded DNA (ssDNA) vector engineered to overcome the limitations of both viral and non-viral gene-editing templates. By combining a customisable double-stranded stem region with a…
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Touchlight’s circular DNA offerings introduces a suite of innovative architectures, mbDNA™, sscDNA, hsscDNA, and dscDNA, designed to overcome the limitations of traditional gene editing tools. These constructs offer enhanced stability,…
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This video introduces Touchlight’s state-of-the-art DNA manufacturing facility, located in the historic Morelands Waterworks in Hampton. Once a vital site for Victorian London’s clean water supply, it has been transformed…
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In this webinar, Touchlight’s Elena Stoyanova, PhD introduces the company’s innovative DNA manufacturing technologies, focusing on their proprietary dbDNA™ (Doggybone DNA) and the newly developed mbDNA™ (MegaBulb DNA ). She…
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CAR T cell therapy has shown remarkable success in treating blood cancers, but current production methods using viral vectors are extremely expensive, limiting patient access. In this groundbreaking study, researchers…
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Recent advancements in non-viral gene editing technologies offer precise genome engineering at significantly reduced costs and biosafety risks compared to viruses. CRISPR is a programmable genome targeting system, which relies…
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