CRISPR HDR Breakthrough with mbDNA™: ssDNA Template Boosts Cell Viability & Scalability CRISPR has transformed our ability to edit genomes, enabling targeted insertions, deletions, and base corrections. Yet…
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mbDNA™ is a synthetic, circular single-stranded DNA (ssDNA) vector engineered to overcome the limitations of both viral and non-viral gene-editing templates. By combining a customisable double-stranded stem region with a…
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Touchlight’s circular DNA offerings introduces a suite of innovative architectures, mbDNA™, sscDNA, hsscDNA, and dscDNA, designed to overcome the limitations of traditional gene editing tools. These constructs offer enhanced stability,…
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This video introduces Touchlight’s state-of-the-art DNA manufacturing facility, located in the historic Morelands Waterworks in Hampton. Once a vital site for Victorian London’s clean water supply, it has been transformed…
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In this webinar, Touchlight’s Elena Stoyanova, PhD introduces the company’s innovative DNA manufacturing technologies, focusing on their proprietary dbDNA™ (Doggybone DNA) and the newly developed mbDNA™ (MegaBulb DNA ). She…
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CAR T cell therapy has shown remarkable success in treating blood cancers, but current production methods using viral vectors are extremely expensive, limiting patient access. In this groundbreaking study, researchers…
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Touchlight’s robust and rapidly scalable manufacturing technology, offers a reliable and effective alternative to pDNA as a knock-in template for CRISPR and, thus, promises to advance non-viral gene therapy. Download…
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Within advanced therapy manufacturing, more and more companies are turning to enzymatically produced DNA as an alternative to plasmid DNA.
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As advanced therapies continue to transform the healthcare landscape, the need for sustainable manufacturing solutions grows more critical. Traditional plasmid DNA (pDNA) production presents costly, resource-intensive challenges, threatening scalability and…
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ELENA STOYANOVA, PH.D. & TOM ADIE, PH.D. Touchlight is at the forefront of innovation in gene editing technology with our groundbreaking MegaBulb DNA (mbDNA). This novel, circular, single-stranded DNA template…
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