This application note highlights the advantages of dbDNA™, a linear, enzymatically amplified DNA construct, as a cell-free alternative to plasmid DNA (pDNA) for lentiviral vector (LVV) production. Manufactured under GMP…
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In this session, Elena Stoyanova, PhD (Touchlight) introduces mbDNA™ (Megabulb DNA), a novel single-stranded circular DNA template featuring a customizable stem region and fully user-defined sequence. Chesney Michels, PhD (ElevateBio)…
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Touchlight announced today that its proprietary z- dbDNA™ technology is to be utilised as a critical starting material in the manufacture of a cutting-edge gene therapy for a US-based clinical…
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Touchlight, a pioneering leader in DNA manufacturing technologies, has been named the 2025 FOYA Category Winner for Innovation in the International Society for Pharmaceutical Engineering (ISPE) Facility of the Year…
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MegaBulb DNA: Enabling better non-viral gene therapy with mbDNA – a cell-free circular ssDNA
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Touchlight’s dbDNA™ enables fast, scalable GMP-grade AAV production with fewer impurities and no bacterial sequences, confirmed by nanopore sequencing.
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mbDNA™ is a groundbreaking non-viral gene-editing technology with a unique circular single-stranded DNA design, engineered for high HDR efficiency and enhanced knock-in performance in immune and stem cells. Compatible with…
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Touchlight Introduces mbDNA™: A “best-in-class" circular single stranded DNA (ssDNA) platform enabling superior gene editing Published: 30 July 2025Touchlight, a pioneer in cell-free DNA innovation, is proud to announce the…
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mbDNA™ is a synthetic, circular single-stranded DNA (ssDNA) vector engineered to overcome the limitations of both viral and non-viral gene-editing templates. By combining a customisable double-stranded stem region with a…
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Touchlight’s circular DNA offerings introduces a suite of innovative architectures, mbDNA™, sscDNA, hsscDNA, and dscDNA, designed to overcome the limitations of traditional gene editing tools. These constructs offer enhanced stability,…
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