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Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model

By July 8, 2025Resources1 min read
Whitepaper
4 mins
DNA Vaccines

Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model

Learn how doggybone DNA (dbDNA™) vaccines offer a safe, scalable alternative to plasmid DNA for cancer immunotherapy, delivering strong immune responses without bacterial components.

Download the full article to learn:

  • How dbDNA™ vaccines can match the immunogenicity of plasmid DNA without bacterial sequences.
  • The potential of cell-free, scalable DNA vaccine production for cancer immunotherapy.
  • Insights into the use of clinically relevant HPV antigens (E6 and E7) in DNA vaccine development.

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