dbDNA
Next‑Generation DNA Template for Genetic Medicines
OVERVIEW
Introducing dbDNA™: A Next-Generation DNA Platform for Genetic Medicines
dbDNA™ is Touchlight’s proprietary enzymatic DNA technology, designed to accelerate the development of genetic therapies. As a cell-free alternative to plasmid DNA, dbDNA enables rapid, scalable, and high-purity DNA production, without the limitations of bacterial fermentation.
Whether you’re working on non-viral gene therapies, RNA, viral vectors, gene editing or DNA vaccines, dbDNA empowers your program with speed, flexibility, and regulatory simplicity.
Why dbDNA™ Matters
Traditional plasmid DNA production relies on fermentation in E. coli — a process that’s slow, complex, and constrained by regulatory and manufacturing challenges. In contrast, cell-free DNA manufacturing offers:
> 5x Faster Production: Multi-gram GMP-grade DNA in weeks, not months
Bacteria-Free: No bacterial sequences, antibiotic resistance genes, or endotoxins
Infinite Payload Capacity: Encode long, complex, and unstable sequences with ease
Streamlined Scale-Up: Manufactured using benchtop equipment with a small footprint
Regulatory Advantage: Simplified pathways for clinical and commercial use
Modality Compatibility: Perfect for viral vector manufacture, non-viral gene therapy, DNA vaccines and gene editing
Backed by Expertise & Infrastructure
Touchlight’s dbDNA platform is built on a foundation of scientific innovation and industrial credibility. Our enzymatic manufacturing process represents a fundamental shift in DNA production, replacing complex biological systems with a cleaner, faster, and more scalable solution.
State‑of‑the‑Art GMP Facilities
11 GMP suites, ultra-low bioburden cleanrooms, EU GMP/ICH Q7 compliant
Global Clinical Impact
dbDNA is powering programs across gene editing, RNA therapeutics, and viral vectors
Trusted by Industry Leaders
Selected by CPI’s RNA Centre of Excellence for both research- and GMP-grade DNA supply
RESOURCES
All About dbDNA™: Discover its Role in Advancing RNA Technologies
dbDNA is rewriting the rules of DNA manufacturing. Discover how our cell-free platform can help you move from discovery to commercialisation, faster, cleaner, and with fewer bottlenecks.
