z- dbDNA
Next‑Generation DNA Template for RNA Therapeutics
OVERVIEW
Introducing z- dbDNA™: A Cell-Free Solution to RNA Manufacturing
As a next-generation DNA template for in vitro transcription (IVT), z- dbDNA enables rapid, flexible RNA development and scale-up to GMP production, without the need for a Master Cell Bank.
That means faster timelines and fewer bottlenecks to bring mRNA-based therapies to the clinic.
Why z‑ dbDNA™ Matters
Touchlight’s enzymatically manufactured z- dbDNA offers key benefits for your RNA workflow, delivering a high purity IVT template with optimal performance and quality attributes.
Skip the master cell bank and move from research to GMP faster
50% increased mRNA yield expected from copy-matched template
Incorporate genes up to 20 kb and long poly(A) tails for advanced constructs
Free of bacterial sequences, cleaner templates mean fewer contaminants and lower downstream burden
Designed for quick transition to GMP production with speed, consistency, and high-quality control
Backed by Expertise & Infrastructure
The regulatory environment and scientific landscape are evolving fast. z‑ dbDNA offers a turnkey, high-performance template solution that aligns with these shifts, pushing RNA medicine towards faster, safer, and more scalable futures.
State‑of‑the‑Art GMP Facilities
Touchlight’s Hampton site features 11 GMP suites, ultra‑low bioburden cleanrooms, and EU GMP/ICH Q7 compliance, capable of producing multiple grams of DNA annually.
Industrial Credibility
Touchlight supports genetic medicine developments across mRNA, AAV, gene editing, and more. Our cell-free platform is already powering clinical programs globally.
Real-World Impact
Selected by CPI’s RNA Centre of Excellence to supply both research- and GMP-grade cell-free DNA for RNA manufacturing.
RESOURCES
All About z- dbDNA™: Discover its Role in Advancing RNA Technologies
Discover how the latest advances in enzymatic DNA can support your work, helping you develop safer, faster, and more scalable genetic medicines.
