MegaBulb DNA: Enabling better non-viral gene therapy with mbDNA – a cell-free circular ssDNA
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Touchlight’s dbDNA™ enables fast, scalable GMP-grade AAV production with fewer impurities and no bacterial sequences, confirmed by nanopore sequencing.
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mbDNA™ is a groundbreaking non-viral gene-editing technology with a unique circular single-stranded DNA design, engineered for high HDR efficiency and enhanced knock-in performance in immune and stem cells. Compatible with…
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Discover how synthetic, backbone-free DNA offers a safer, scalable alternative to traditional plasmid DNA for AAV production, addressing key challenges in transfection efficiency, cost, and impurity control. Download the poster…
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Touchlight’s robust and rapidly scalable manufacturing technology, offers a reliable and effective alternative to pDNA as a knock-in template for CRISPR and, thus, promises to advance non-viral gene therapy. Download…
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Here, we demonstrate that dbDNATM can be optimised for the manufacture of high titre LVV.
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Touchlight’s dbDNA (doggybone DNA) is a novel and disruptive advancement in DNA manufacturing technology, designed to overcome the limitations of traditional plasmid DNA (pDNA) production. Download the poster here: 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Download the poster here
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